Malvern Alachyticalis joining forces with contract services organization Next Breath, which specializes in inhaled product development, to present an interactive workshop at Respiratory Drug Delivery 2013 (RDD 2013), which takes place in Berlin, Germany from 21-24 May 2013.
The workshop, ‘Linking Dissolution and Particle Size via Raman Imaging’, runs on 22 May and examines the application and benefits of morphologically directed Raman spectroscopy for characterizing inhaled products.
演示者将着重于与成分特异性粒径分析的悬浮鼻喷雾剂和吸入药物的体外溶解相关性。该会议将涉及Malvern Panalytical的Morphologi G3-ID的演示，该系统将自动成像与使用拉曼光谱法化学鉴定的化学鉴定结合在一起。yabo214要了解有关研讨会的更多信息，请访问RDD网站：http://www.rddonline.com
The Morphologi G3-ID enables the efficient direction of spectroscopy to particle populations of interest, classified on the basis of particle size and shape. This makes it a valuable tool for the analysis and development of complex, multicomponent inhalation drug dispersions.
Workshop participants will learn how the Morphologi G3-ID helps provide evidence of bioequivalence and can advance the drug validation process through supporting the use of biowavers. Biowavers apply in regulatory drug approval processes where the efficacy and safety sections of the validation process can be approved based on in vitro equivalence testing. Case study evidence will relate the in vitro dissolution behavior of drug product to component-specific particle size data gathered using the Morphologi G3-ID. There will also be guidance on the fundamentals of using this powerful particle characterization technique, including hints and tips on sample preparation and analysis.
通过将粒子成像与拉曼光谱结合在一起，形态G3-ID可以在单个仪器中实现大小，形状和化学识别。能够使用强大的光学技术捕获单个粒子yabo214物种的图像，能够测量尺寸范围为0.5微米的粒子范围为0.5微米。所得数据可以根据大小和形状的尺寸和形状进行分类，并在拉曼光谱法分析之前，提供化学表征。yabo214这些能力使形态G3-ID成为开发悬浮鼻喷雾剂和干粉吸入器配方的强大工具，在该配方中，它可以在混合物内实现有针对性的定量，物理和化学表征。