Sysmex FPIA-3000 Flow Particle Image Analyzer Improves the Manufacture of Inhaled Medications

The Sysmex FPIA-3000 Flow Particle Image Analyzer fromMalvern Alachytical被用来帮助改善通过雾化器管理的吸入药物的生产。通过对悬浮液中颗粒的大小和形状进行快速,可重复的测量,可以在制造过程中使用SYSMEX FPIA-3000来检测在药物给药过程中可能无法yabo214分散的大颗粒的存在和性质。

Modifying the process to eliminate the source of these particles improves the efficiency of drug delivery since larger particles will not be successfully emitted by the nebuliser or deposited in the lung.

The Sysmex FPIA-3000 uses advanced imaging technology to provide size and shape distributions for each sample measured, along with a scattergram which depicts the size versus shape of the particles. If large particles are identified during the manufacturing process of inhalation drug suspensions, their recorded images can be viewed to enable distinction between primary particles, loose agglomerates and hard aggregates. By fully characterizing problematic particles, it becomes possible to determine whether the energy supplied by the nebuliser is likely to be sufficient for effective dispersion and, if not, to distinguish where in the process the problem arises. For example, large primary particles may be an indication of ineffective homogenization.

Analysis of a sample on the FPIA- 3000 takes only 2.5 minutes and repeat measurements can easily be set up in the standard operating procedure (SOP). This combination of features, speed and accuracy make this the ideal system for both pharmaceutical research and quality control.

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    Malvern Alachytical。(2019, February 10). Sysmex FPIA-3000 Flow Particle Image Analyzer Improves the Manufacture of Inhaled Medications. AZoM. Retrieved on March 10, 2023 from //www.washintong.com/news.aspx?newsID=20515.

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